Non-insulin-dependent diabetes mellitus (NIDDM) is associated with metabolic and hematological changes that may lead to complications. To study the physiological and biochemical blood parameters in male NIDDM patients in Najaf, Iraq. 40 male patients with NIDDM, aged 38–70 years, were examined over a three-month period after confirmation of NIDDM. Physiological parameters included hemoglobin concentration, total and differential white blood cell count, and erythrocyte sedimentation rate (ESR). Biochemical parameters included serum glucose and total cholesterol. We compared them with 40 healthy males. Data are presented as mean ± standard error, and significance was tested at p<0.05. Patients showed a significant increase (p<0.01) in total white blood cell count and erythrocyte sedimentation rate compared to the control group. Serum glucose and total cholesterol levels also increased significantly (p<0.01). No significant changes were observed in hemoglobin concentration and some white blood cell subsets. Differential counts revealed neutrophilia and a relative decrease in lymphocytes in the patients. The Iraqi patients who have non-type 2 diabetes show significant changes in biochemical parameters, and hematological, particularly hyperglycemia, dyslipidemia, and inflammation.
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