Proceedings of International Conference on Applied Innovation in IT  ·  2026/03/31  ·  Vol. 14  ·  Issue 1  ·  pp. 849–857
Anti-Cancer Activity of Titanium-Copper Alloy Coated with Silver Nanoparticles on Reduced Graphene Oxide Against Oral Squamous Carcinoma Cells
Mayada Faisel Khalil, Farah Tariq Muhammad Noori and Sabah Anwer Salman
📄 Download PDF DOI: 10.25673/123646
Abstract
Ti alloys are frequently utilized in fields that have a significant impact like medicine, chemistry, and physics because of their exceptional properties. The properties of titanium alloys are affected by their composition and microstructure. This investigation intended to investigate the effects of different concentrations of copper 0, 0.5, 2.5, and 5 wt% on the cancerous cell line of the mouth coated with and without silver nanoparticles- Reduced graphene oxide (AgNps- rGO) sheets using Plus laser technology. The morphology and structural properties of the titanium-copper alloys were evaluated using scanning electron microscopy (SEM) and X-ray diffraction (XRD). The result show the weight percentage of copper and the coating layer of coated alloys were studied, 54% of the Oral squamous cell carcinoma cell line (OSCC) was killed by the (Ti-0%Cu) coated alloy, while 79% of the OSCC cell line was killed by the (Ti-5%Cu) coated alloy.The XRD results of the alloy before and after coating showed that the diffraction peaks are for the α-Ti phase, as well as slight peaks for the metallic Ti2Cu phase, but no β-Ti peaks could be found. The (SEM) of the alloys prior to coating revealed that the pure titanium is uniformly dispersed throughout but the SEM images of the coated alloys revealed that the silver nanoparticles were distributed in a range of 20-26 nm with graphene oxide in a range of less than 100 nm.
Keywords
Ti-Cu Alloy Metallurgy PLD Hummer’s Method Reduced Graphene Oxide Oral Squamous Carcinoma Cell Line.
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